{"id":2012,"date":"2019-06-04T11:57:01","date_gmt":"2019-06-04T02:57:01","guid":{"rendered":"https:\/\/www.zoology.or.jp\/?p=2012"},"modified":"2019-06-04T11:59:35","modified_gmt":"2019-06-04T02:59:35","slug":"%e5%b9%b3%e6%88%9029%e5%b9%b4%e5%ba%a6%e6%97%a5%e6%9c%ac%e5%8b%95%e7%89%a9%e5%ad%a6%e4%bc%9a%e5%ad%a6%e4%bc%9a%e8%b3%9e%e3%81%ae%e9%81%b8%e8%80%83%e7%b5%90%e6%9e%9c%e3%83%bb%e5%8f%97%e8%b3%9e%e8%80%85","status":"publish","type":"post","link":"https:\/\/www.zoology.or.jp\/english\/archives\/2012","title":{"rendered":"\u5e73\u621029\u5e74\u5ea6\u65e5\u672c\u52d5\u7269\u5b66\u4f1a\u5b66\u4f1a\u8cde\u306e\u9078\u8003\u7d50\u679c\u30fb\u53d7\u8cde\u8005\u8981\u65e8"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u516c\u76ca\u793e\u56e3\u6cd5\u4eba\u3000\u65e5\u672c\u52d5\u7269\u5b66\u4f1a\u7406\u4e8b\u4f1a\u306f\u30012018\u5e746\u67082\u65e5\uff08\u91d1\uff09\u7406\u4e8b\u4f1a\u3092\u958b\u50ac\u3057\u3001\u5b66\u4f1a\u8cde\u7b49\u9078\u8003\u59d4\u54e1\u4f1a\u306e\u63a8\u85a6\u5019\u88dc\u8005\u3092\u57fa\u306b\u3001\u5404\u8cde\u53d7\u8cde\u8005\u306e\u5be9\u8b70\u884c\u3044\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u5e73\u621029\u5e74\u5ea6\u65e5\u672c\u52d5\u7269\u5b66\u4f1a\u306e\u5404\u8cde\u3092\u4e0b\u8a18\u306e\u3088\u3046\u306b\u6c7a\u5b9a\u3057\u307e\u3057\u305f\u3002\u6388\u8cde\u5f0f\u3001\u307e\u305f\u5b66\u4f1a\u8cde\u3001\u5968\u52b1\u8cde\u53d7\u8cde\u8005\u8b1b\u6f14\u306f\u30019\u670822\u65e5\u5bcc\u5c71\u770c\u6c11\u4f1a\u9928\u306b\u3066\u884c\u308f\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"text-align:right\">\u516c\u76ca\u793e\u56e3\u6cd5\u4eba\u3000\u65e5\u672c\u52d5\u7269\u5b66\u4f1a<br>\n\u4f1a\u9577\u3000\u5ca1\u3000\u826f\u9686<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u65e5\u672c\u52d5\u7269\u5b66\u4f1a\u8cde<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">\u4f0a\u85e4\u60a6\u6717(\u3044\u3068\u3046\u3000\u3048\u3064\u308d\u3046)<br>\n\u65e9\u7a32\u7530\u5927\u5b66\u3001\u6559\u80b2\u30fb\u7dcf\u5408\u79d1\u5b66\u5b66\u8853\u9662\u3001\u6559\u6388<br>\n\u300e\u8edf\u4f53\u52d5\u7269\u8179\u8db3\u985e\u306e\u5b66\u7fd2\u8a18\u61b6\u6a5f\u69cb\u306e\u89e3\u660e\u300f<\/h4>\n\n\n\n<h5 class=\"wp-block-heading\">\u53d7\u8cde\u7406\u7531<\/h5>\n\n\n\n<p class=\"wp-block-paragraph\"> \u3000\u4f0a\u85e4\u60a6\u6717\u6c0f\u306f\u9577\u5e74\u306b\u308f\u305f\u308a\u3001\u8edf\u4f53\u52d5\u7269\u8179\u8db3\u985e\u306e\u5b66\u7fd2\u8a18\u61b6\u6a5f\u69cb\u3092\u7814\u7a76\u3057\u3066\u304d\u307e\u3057\u305f\u3002\u30ab\u30f3\u30c7\u30eb\u4ee5\u6765\u306e\u4f1d\u7d71\u304c\u3042\u308b\u3053\u306e\u5206\u91ce\u3067\u3001\u4f0a\u85e4\u6c0f\u306f\u521d\u3081\u3066\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u3092\u5bfe\u8c61\u306b\u9078\u3073\u3001\u305d\u306e\u5473\u899a\u5acc\u60aa\u5b66\u7fd2\u3068\u3044\u3046\u884c\u52d5\u3092\u4f7f\u3063\u3066\u3001\u304d\u308f\u3081\u3066\u30e6\u30cb\u30fc\u30af\u306a\u7814\u7a76\u3092\u9032\u3081\u3066\u304d\u307e\u3057\u305f\u3002\u6700\u8fd1\u306e\u5927\u304d\u306a\u6210\u679c\u3068\u3057\u3066\u306f\u3001\u5473\u899a\u5acc\u60aa\u5b66\u7fd2\u306b\u304a\u3051\u308b\u9577\u671f\u8a18\u61b6\u306e\u5f62\u6210\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u7269\u8cea\u304c\u6c7a\u5b9a\u7684\u306a\u5f79\u5272\u3092\u679c\u305f\u3059\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u305f\u3053\u3068\u304c\u6319\u3052\u3089\u308c\u307e\u3059\u3002\u8a18\u61b6\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u7269\u8cea\u306e\u95a2\u4fc2\u306b\u3064\u3044\u3066\u306e\u4e00\u9023\u306e\u7814\u7a76\u304c\u9806\u8abf\u306b\u9032\u5c55\u3057\u305f\u80cc\u666f\u306b\u306f\u30011999\u5e74\u306b\u65e5\u672c\u52d5\u7269\u5b66\u4f1a\u5968\u52b1\u8cde\u3092\u53d7\u8cde\u3055\u308c\u305fCerebral Giant Cell\uff08CGC\uff09\u3068\u3044\u3046\u30cb\u30e5\u30fc\u30ed\u30f3\u306e\u767a\u898b\u306b\u59cb\u307e\u308b\u3001\u4f0a\u85e4\u6c0f\u4e00\u6d41\u306e\u81a8\u5927\u304b\u3064\u7cbe\u7dfb\u306a\u5b9a\u91cf\u7684\u7814\u7a76\u304c\u3042\u308a\u307e\u3059\u3002\u4f0a\u85e4\u6c0f\u306f\u3001\u5358\u4e00\u306eCGC\u30cb\u30e5\u30fc\u30ed\u30f3\u3067CREB\u907a\u4f1d\u5b50\u3084\u907a\u4f1d\u5b50\u7523\u7269\u3092\u5b9a\u91cf\u5206\u6790\u3059\u308b\u65b9\u6cd5\u3092\u88c5\u7f6e\u306e\u958b\u767a\u304b\u3089\u624b\u304c\u3051\u3001\u305d\u308c\u3092\u81ea\u8eab\u306e\u7814\u7a76\u306b\u898b\u4e8b\u306b\u751f\u304b\u3057\u3001\u65e5\u672c\u52d5\u7269\u5b66\u4f1a\u8cde\u3092\u6388\u4e0e\u3059\u308b\u306b\u3075\u3055\u308f\u3057\u3044\u529f\u7e3e\u3092\u3042\u3052\u307e\u3057\u305f\u3002\u3000<\/p>\n\n\n\n<h5 class=\"wp-block-heading\">\u53d7\u8cde\u8005\u8981\u65e8<\/h5>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000\u79c1\u304c\u8edf\u4f53\u52d5\u7269\u8179\u8db3\u985e\u3092\u5b9f\u9a13\u52d5\u7269\u3068\u3057\u3066\u5229\u7528\u3059\u308b\u6700\u521d\u306e\u304d\u3063\u304b\u3051\u306f\u3001\u30a2\u30e1\u30ea\u30abNIH\u306eDaniel Alkon\u5148\u751f\u306e\u7814\u7a76\u5ba4\u306bVisiting Fellow\u3068\u3057\u3066\u7559\u5b66\u3057\u3001\u30a6\u30df\u30a6\u30b7\uff08<em>Hermissenda<\/em>\uff09\u306e\u5b66\u7fd2\u8a18\u61b6\u7814\u7a76\u306b\u5f93\u4e8b\u3059\u308b\u30c1\u30e3\u30f3\u30b9\u3092\u9802\u3044\u305f\u6642\u3067\u3042\u3063\u305f\u3002\u305d\u3057\u3066\u300120\u4ee3\u5f8c\u534a\u30fb30\u4ee3\u524d\u534a\u306e\u82e5\u3044\u6642\u671f\u3092\u3001Woods Hole\u306b\u3042\u308bMarine Biological Laboratory\u3067\u306e\u975e\u5e38\u306b\u6fc3\u5bc6\u306a\u7814\u7a76\u3001\u5317\u7c73\u795e\u7d4c\u79d1\u5b66\u5b66\u4f1a\uff08SfN\uff09\u3067\u306e\u6fc0\u3057\u3044\u3084\u308a\u53d6\u308a\u306a\u3069\u3001\u5927\u5909\u523a\u6fc0\u7684\u306a\u6642\u7a7a\u9593\u306b\u8eab\u3092\u7f6e\u3051\u305f\u3053\u3068\u304c\u3001\u672c\u5f53\u306b\u5e78\u904b\u3060\u3063\u305f\u3068\u601d\u3046\uff08Ito<em>et al.<\/em>, 1994,&nbsp;<em>J. Neurochem.<\/em>\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">1993\u5e74\uff08\u5e73\u62105\u5e74\uff09\u306b\u5317\u6d77\u9053\u5927\u5b66\u7406\u5b66\u90e8\u306b\u8077\u3092\u5f97\u3066\u5e30\u56fd\u5f8c\u3001\u3055\u3066\u3069\u306e\u5b9f\u9a13\u52d5\u7269\u3092\u4f7f\u304a\u3046\u304b\u3068\u60a9\u3093\u3067\u3044\u305f\u3068\u3053\u308d\u3001\u6240\u5c5e\u8b1b\u5ea7\u306e\u6559\u6388\u3067\u3042\u3063\u305f\u6d66\u91ce\u660e\u592e\u5148\u751f\u304b\u3089\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\uff08<em>Lymnaea<\/em>\uff09\u3092\u3054\u7d39\u4ecb\u9802\u3044\u305f\u3002<em>Lymnaea stagnalis<\/em>\u306f\u82f1\u8a9e\u540d\u3067great pond snail\u3001\u548c\u540d\u3067\u30e8\u30fc\u30ed\u30c3\u30d1\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u3068\u547c\u3070\u308c\u308b\u3002\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u306e\u6700\u5927\u306e\u7279\u5fb4\u306f\u3001\u5909\u614b\u304c\u5375\u306e\u4e2d\u3067\u5b8c\u4e86\u3057\u3066\u304a\u308a\u3001\u3059\u306a\u308f\u3061\u5b75\u5316\u3057\u305f\u6642\u70b9\u3067\u3001\u6210\u4f53\u306e\u30df\u30cb\u30c1\u30e5\u30a2\u7248\u306b\u306a\u3063\u3066\u3044\u308b\u3053\u3068\u3067\u3042\u308b\u3002\u30a2\u30e1\u30d5\u30e9\u30b7\u3084\u30a6\u30df\u30a6\u30b7\u306f\u5b75\u5316\u5f8c\u306b\u3082\u5909\u614b\u3092\u3059\u308b\u306e\u3067\u98fc\u80b2\u304c\u304b\u306a\u308a\u5384\u4ecb\u3067\u3042\u308a\u3001\u6210\u4f53\u3092\u63a1\u96c6\u3059\u308b\u3068\u3053\u308d\u304b\u3089\u5b9f\u9a13\u3092\u59cb\u3081\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3002\u3057\u304b\u3057\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u306e\u5834\u5408\u306f\u3001\u81ea\u3089\u306e\u5b9f\u9a13\u5ba4\u3067\u30e9\u30a4\u30d5\u30b5\u30a4\u30af\u30eb\u3092\u56de\u3059\u3053\u3068\u304c\u53ef\u80fd\u3067\u3042\u308a\u3001\u4e00\u5e74\u4e2d\u7814\u7a76\u304c\u3067\u304d\u308b\uff08\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u306e\u7814\u7a76\u6210\u679c\u3092\u521d\u3081\u3066<em>Zool. Sci.<\/em>\u3067\u767a\u8868\u3055\u305b\u3066\u9802\u3044\u305f\u3068\u304d\u306e\u8ad6\u6587\uff1aKojima<em>et al.<\/em>, 1996,&nbsp;<em>Zool. Sci.<\/em>\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u306f\u3001\u55dc\u597d\u6027\u306e\u3042\u308b\u30b7\u30e7\u7cd6\u306b\u7d9a\u3044\u3066\u5fcc\u907f\u6027\u306e\u5869\u5316\u30ab\u30ea\u30a6\u30e0\u307e\u305f\u306f\u96fb\u6c17\u30b7\u30e7\u30c3\u30af\u3092\u63d0\u793a\u3059\u308b\u3068\u3001\u30b7\u30e7\u7cd6\u306b\u3088\u3063\u3066\u8a98\u767a\u3055\u308c\u308b\u306f\u305a\u306e\u5480\u56bc\uff08\u305d\u3057\u3083\u304f\uff09\u904b\u52d5\u3092\u8d77\u3053\u3055\u306a\u304f\u306a\u308b\u3002\u308f\u308c\u308f\u308c\u306f\u3001\u3053\u308c\u3092\u4e00\u7a2e\u306e\u300c\u5473\u899a\u5acc\u60aa\u5b66\u7fd2\u300d\u3060\u3068\u8003\u3048\u305f\u3002\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u306e\u5473\u899a\u5acc\u60aa\u5b66\u7fd2\u306f\u4e00\u5ea6\u899a\u3048\u305f\u3089\uff11\u304b\u6708\u4ee5\u4e0a\u306e\u9577\u304d\u306b\u308f\u305f\u308a\u8a18\u61b6\u3059\u308b\u300c\u9577\u671f\u8a18\u61b6\u300d\u3067\u3042\u308b\u3002\u305d\u306e\u5f8c\u3001\u3053\u306e\u5473\u899a\u5acc\u60aa\u5b66\u7fd2\u306b\u95a2\u3059\u308b\u4e00\u9023\u306e\u751f\u7406\u5b66\u7684\u30fb\u7d44\u7e54\u5b66\u7684\u7814\u7a76\u3092\u901a\u3058\u3066\u30011999\u5e74\uff08\u5e73\u621011\u5e74\uff09\u306b\u65e5\u672c\u52d5\u7269\u5b66\u4f1a\u300c\u5968\u52b1\u8cde\u300d\u3092\u9802\u6234\u3059\u308b\u306b\u81f3\u3063\u305f\uff08\u5968\u52b1\u8cde\u3092\u9802\u3044\u305f\u6642\u306ereview\u8ad6\u6587\uff1aIto<em>et al.<\/em>, 1999,&nbsp;<em>Zool. Sci.<\/em>\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000\u305d\u306e\u5f8c\u3001\u308f\u308c\u308f\u308c\u306f\u9577\u671f\u8a18\u61b6\u5f62\u6210\u5f8c\u306b\u3069\u306e\u907a\u4f1d\u5b50\u304c\u767a\u73fe\u3057\u3066\u304f\u308b\u306e\u304b\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u305f\u3081\u306b\u3001\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u306eDNA\u30c1\u30c3\u30d7\u3092\u81ea\u3089\u4f5c\u88fd\u3057\u7814\u7a76\u3092\u91cd\u306d\u305f\u3002\u3053\u306e\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u306eDNA\u30c1\u30c3\u30d7\u306e\u4f5c\u88fd\u306b\u3064\u3044\u3066\u306f\u3001\u5f53\u6642\u306e\u5317\u6d77\u9053\u5927\u5b66\u306b\u306f\u5b89\u4f4f\u85ab\u5148\u751f\u304c\u304a\u3089\u308c\u3001\u5b89\u4f4f\u5148\u751f\u3068\u5171\u540c\u7814\u7a76\u3055\u305b\u3066\u9802\u3044\u305f\u3053\u3068\u304c\u3001\u5927\u304d\u304f\u5f71\u97ff\u3057\u3066\u3044\u308b\u3002\u5f53\u6642\u3092\u601d\u3044\u8d77\u3053\u3059\u3068\u300c\u7db2\u7f85\u7684\u306b\u8abf\u3079\u308b\u300d\u3053\u3068\u304c\u6d41\u884c\u3067\u3042\u3063\u305f\u3002\u305d\u306e\u7814\u7a76\u6210\u679c\u3068\u3057\u3066\u3001\u5b66\u7fd2\u5f8c\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\uff08molluscan insulin-related peptide\uff1aMIP\uff09\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u304c\u8133\u5185\u3067\u4ea2\u9032\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3067\u304d\u305f\u3002\u3057\u304b\u3057\u6b63\u76f4\u3001\u305d\u306e\u5f53\u6642\u306f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\u306e\u767a\u73fe\u4ea2\u9032\u306e\u751f\u7269\u5b66\u7684\u610f\u5473\u306f\u4f55\u306a\u306e\u304b\u304c\u3001\u7406\u89e3\u3067\u304d\u306a\u3044\u3067\u3044\u305f\uff08Azami<em>et al.<\/em>, 2006,&nbsp;<em>J. Neurosci. Res.<\/em>\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30002006\u5e74\uff08\u5e73\u621018\u5e74\uff09\u306b\u3001\u79c1\u306f\u5317\u6d77\u9053\u5927\u5b66\u304b\u3089\u5fb3\u5cf6\u6587\u7406\u5927\u5b66\u9999\u5ddd\u85ac\u5b66\u90e8\u306b\u7570\u52d5\u3057\u3001\u305d\u306e\u7570\u52d5\u5f8c\u306b\u5358\u96e2\u3057\u305f\u8133\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\u3092\u76f4\u63a5\u6295\u4e0e\u3059\u308b\u3053\u3068\u3067\u3001\u5480\u56bc\u904b\u52d5\u306b\u4fc2\u308b\u795e\u7d4c\u56de\u8def\u3078\u306e\u5f71\u97ff\u3092\u8abf\u3079\u305f\u3002\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\u3001\u307e\u305f\u306f\u307b\u4e73\u985e\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u6295\u4e0e\u3057\u305f\u3068\u3053\u308d\u3001\u5480\u56bc\u904b\u52d5\u306b\u4fc2\u308b\u7279\u5b9a\u306e\u795e\u7d4c\u56de\u8def\u3067\u300c\u9577\u671f\u5897\u5f37\u300d\u69d8\u306e\u53cd\u5fdc\u304c\u78ba\u8a8d\u3067\u304d\u305f\u3002\u9577\u671f\u5897\u5f37\u306f\u4e00\u822c\u7684\u306b\u306f\u5b66\u7fd2\u8a18\u61b6\u306e\u795e\u7d4c\u57fa\u76e4\u3068\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u304a\u308a\u3001\u3059\u306a\u308f\u3061\u4f53\u5185\u306e\u7cd6\u6fc3\u5ea6\u8abf\u7bc0\u306a\u3069\u306b\u95a2\u308f\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\u304c\u3001\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u306e\u8133\u5185\u306e\u5473\u899a\u5acc\u60aa\u5b66\u7fd2\u6a5f\u69cb\u306b\u3082\u91cd\u8981\u306a\u306f\u305f\u3089\u304d\u3092\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u305f\u3002\u3055\u3089\u306b\u306f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u53d7\u5bb9\u4f53\u306e\u7d50\u5408\u90e8\u4f4d\u306e\u69cb\u9020\u304c\u3001\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u3068\u307b\u4e73\u985e\u3068\u3067\u76f8\u540c\u3067\u3042\u308b\u3053\u3068\u306b\u7740\u76ee\u3057\u3001\u305d\u306e\u7d50\u5408\u90e8\u4f4d\u3092\u30a8\u30d4\u30c8\u30fc\u30d7\u3068\u3059\u308b\u307b\u4e73\u985e\u306e\u6297\u4f53\u3092\u6ce8\u5165\u3057\u305f\u3068\u3053\u308d\u3001\u3053\u306e\u9577\u671f\u5897\u5f37\u69d8\u306e\u5fdc\u7b54\u306f\u6d88\u53bb\u3055\u308c\u305f\u3002\u307e\u305f\u3001\u6297\u4f53\u3092\u500b\u4f53\u306b\u6ce8\u5165\u3059\u308b\u3068\u3001\u5473\u899a\u5acc\u60aa\u5b66\u7fd2\u306e\u9577\u671f\u8a18\u61b6\u5f62\u6210\u3082\u963b\u5bb3\u3055\u308c\u305f\u3002\u3053\u306e\u3088\u3046\u306b\u5473\u899a\u5acc\u60aa\u5b66\u7fd2\u6a5f\u69cb\u306b\u304a\u3051\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\u306e\u5fc5\u8981\u5341\u5206\u6761\u4ef6\u304c\u6574\u3063\u305f\uff08Murakami<em>et al.<\/em>, 2013,&nbsp;<em>J. Neurosci.<\/em>\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3000\u4e00\u65b9\u3067\u308f\u308c\u308f\u308c\u306f\u3001\u8efd\u5ea6\u306a\u98e2\u9913\u72b6\u614b\u306b\u304a\u304b\u308c\u305f\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u306f\u5473\u899a\u5acc\u60aa\u5b66\u7fd2\u306e\u6210\u7e3e\u304c\u826f\u3044\u304c\u3001\u5f37\u5ea6\u306a\u98e2\u9913\u72b6\u614b\u306e\u5834\u5408\u306f\u5b66\u7fd2\u8a18\u61b6\u304c\u6210\u7acb\u3057\u306a\u3044\u3053\u3068\u3092\u3001\u7d4c\u9a13\u7684\u306b\u77e5\u3063\u3066\u3044\u305f\u3002\u305d\u3053\u3067\u4f5c\u696d\u4eee\u8aac\u3068\u3057\u3066\u3001\u5f37\u5ea6\u306a\u98e2\u9913\u72b6\u614b\u3067\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\u6fc3\u5ea6\u304c\u4f4e\u304f\u306a\u3063\u3066\u3044\u308b\u3068\u4e88\u60f3\u3057\u305f\u3002\u5b9f\u969b\u306b\u3001\u5f37\u5ea6\u306a\u98e2\u9913\u72b6\u614b\u306e\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\u3092\u6ce8\u5165\u3057\u3066\u6fc3\u5ea6\u3092\u4e0a\u6607\u3055\u305b\u3066\u307f\u305f\u3068\u3053\u308d\u3001\u5b66\u7fd2\u8a18\u61b6\u306e\u6210\u7e3e\u304c\u6539\u5584\u3055\u308c\u308b\u3053\u3068\u304c\u5206\u3063\u305f\u3002\u3053\u306e\u3088\u3046\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\u304c\u5b66\u7fd2\u8a18\u61b6\u6a5f\u69cb\u306e\u9375\u3092\u63e1\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u306f\u3063\u304d\u308a\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u5f37\u5ea6\u306a\u98e2\u9913\u72b6\u614b\u306e\u5834\u5408\u306b\u304a\u304b\u308c\u305f\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u306f\u3001\u672c\u5f53\u306b\u5473\u899a\u5acc\u60aa\u5b66\u7fd2\u3092\u7fd2\u5f97\u3057\u3066\u3044\u306a\u3044\u306e\u304b\u3001\u3068\u3044\u3046\u554f\u984c\u306b\u8feb\u3063\u305f\u3002\u305d\u3053\u3067\u3001\u3044\u308d\u3044\u308d\u306a\u6761\u4ef6\u3092\u632f\u3063\u3066\u307f\u305f\u3068\u3053\u308d\u3001\u5f37\u5ea6\u306a\u98e2\u9913\u72b6\u614b\u306e\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u306b\u5473\u899a\u5acc\u60aa\u5b66\u7fd2\u3092\u65bd\u3057\u3001\u305d\u306e\u5f8c\u3057\u3070\u3089\u304f\u98fd\u98df\u72b6\u614b\u306b\u3057\u3066\u304b\u3089\u3001\u518d\u5ea6\u3001\u98e2\u9913\u72b6\u614b\u306b\u3059\u308b\u3068\u3001\u9a5a\u304f\u3079\u304d\u3053\u3068\u306b\u5473\u899a\u5acc\u60aa\u5b66\u7fd2\u304c\u6210\u7acb\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u3063\u305f\u3002\u5473\u899a\u5acc\u60aa\u5b66\u7fd2\u306f\u3001\u7c21\u5358\u306b\u8ff0\u3079\u308b\u3068\u300c\u7f70\u304c\u4e0e\u3048\u3089\u308c\u308b\u3053\u3068\u3067\u597d\u304d\u306a\u7269\u3092\u98df\u3079\u3089\u308c\u306a\u304f\u306a\u308b\u300d\u5b66\u7fd2\u3067\u3042\u308a\u3001\u3059\u306a\u308f\u3061\u3001\u5b66\u7fd2\u3057\u305f\u6642\u70b9\u3067\u5f37\u5ea6\u306b\u8179\u304c\u6e1b\u3063\u3066\u3044\u308b\u3068\u3001\u4eee\u306b\u5b66\u7fd2\u3057\u3066\u3044\u3066\u3082\u300c\u80cc\u306b\u8179\u306f\u4ee3\u3048\u3089\u308c\u305a\u300d\u98df\u3079\u3066\u306f\u3044\u3051\u306a\u3044\u7269\u3092\u98df\u3079\u3066\u3057\u307e\u3046\u3002\u305d\u3057\u3066\u3001\u305d\u306e\u3042\u3068\u3057\u3070\u3089\u304f\u3057\u3066\u304b\u3089\u518d\u3073\u98e2\u9913\u306b\u306a\u308b\u3068\u3001\u5473\u899a\u5acc\u60aa\u5b66\u7fd2\u3092\u601d\u3044\u51fa\u3057\u3066\u3001\u98df\u3079\u3066\u306f\u3044\u3051\u306a\u3044\u7269\u3092\u98df\u3079\u306a\u3044\u3088\u3046\u306b\u306a\u308b\u308f\u3051\u3060\u3002\u3055\u3089\u306b\u306f\u3001\u3053\u306e\u518d\u5ea6\u306e\u98e2\u9913\u306e\u4ee3\u308f\u308a\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\u3092\u4e0e\u3048\u308b\u3053\u3068\u3067\u8a18\u61b6\u306e\u60f3\u8d77\u304c\u53ef\u80fd\u3067\u3042\u3063\u305f\u3002\u3064\u307e\u308a\u3001\u52d5\u7269\u306f\u5b66\u7fd2\u8a18\u61b6\u6a5f\u69cb\u3092\u4e00\u3064\u306e\u5b9a\u578b\u7684\u306a\u5f62\u3067\u5229\u7528\u3057\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u500b\u4f53\u304c\u4e0a\u624b\u306b\u751f\u5b58\u3059\u308b\u305f\u3081\u306b\u3001\u67d4\u8edf\u306b\u5229\u7528\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u3063\u305f\uff08Ito<em>et al.<\/em>, 2015,&nbsp;<em>J. Exp. Biol.<\/em>\uff09\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30002016\u5e74\uff08\u5e73\u621028\u5e74\uff09\u306b\u3001\u4eca\u5ea6\u306f\u65e9\u7a32\u7530\u5927\u5b66\u306e\u6559\u80b2\u5b66\u90e8\u7406\u5b66\u79d1\u751f\u7269\u5b66\u5c02\u4fee\u306b\u7570\u52d5\u3057\u3001\u65b0\u305f\u306a\u7814\u7a76\u3092\u5c55\u958b\u3057\u59cb\u3081\u305f\u3002\u73fe\u6642\u70b9\u3067\u3001\u5b66\u7fd2\u88c5\u7f6e\u306e\u5b8c\u5168\u81ea\u52d5\u5316\u306b\u6210\u529f\u3057\u3001\u98e2\u9913\u72b6\u614b\u3068\u5b66\u7fd2\u6210\u7e3e\u3001\u3055\u3089\u306b\u306f\u30e2\u30ce\u30a2\u30df\u30f3\u306e\u6fc3\u5ea6\u5909\u5316\u3068\u306e\u95a2\u9023\u3082\u660e\u3089\u304b\u306b\u3067\u304d\u305f\uff08Aonuma<em>et al.<\/em>, 2017,&nbsp;<em>Neurobiol. Learn. Mem.<\/em>\uff09\u3002\u307e\u305f\u5b66\u7fd2\u80fd\u529b\u306e\u5730\u57df\u5dee\uff08\u56fd\u5225\u306e\u5dee\uff09\u306b\u3064\u3044\u3066\u3082\u7814\u7a76\u3092\u9042\u884c\u3057\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u5b66\u4f1a\u8cde\u53d7\u8cde\u306f\u3001\u30a2\u30e1\u30ea\u30abNIH\u6642\u4ee3\u3001\u5317\u6d77\u9053\u5927\u5b66\u6642\u4ee3\u3001\u5fb3\u5cf6\u6587\u7406\u5927\u5b66\u6642\u4ee3\u305d\u3057\u3066\u73fe\u5728\u306e\u65e9\u7a32\u7530\u5927\u5b66\u306b\u304a\u3051\u308b\u3001\u30e1\u30f3\u30bf\u30fc\u3001\u540c\u50da\u306e\u7814\u7a76\u8005\u306e\u65b9\u3005\u3001\u9662\u751f\u30fb\u5b66\u751f\u306e\u7686\u3055\u3093\u3001\u30dd\u30b9\u30c9\u30af\u306e\u7686\u3055\u3093\u3001\u6280\u8853\u88dc\u4f50\u54e1\u306e\u7686\u3055\u3093\u3001\u79d8\u66f8\u3055\u3093\u3001\u305d\u3057\u3066\u591a\u6570\u306e\u56fd\u5185\u5916\u306e\u5171\u540c\u7814\u7a76\u8005\u304b\u3089\u306e\u3054\u6307\u5c0e\u30fb\u3054\u5354\u529b\u306b\u3088\u308b\u3082\u306e\u3060\u3068\u6df1\u304f\u611f\u8b1d\u3057\u3066\u3044\u308b\u3002\u305d\u308c\u306b\u52a0\u3048\u3066\u3001100\u5e74\u4ee5\u4e0a\u3082\u7d9a\u304f\u30e2\u30ce\u30a2\u30e9\u30ac\u30a4\u3092\u7528\u3044\u305f\u751f\u7269\u5b66\u7814\u7a76\u306e\u6b74\u53f2\u304c\u3001\u6211\u3005\u306e\u7814\u7a76\u3092\u5f8c\u62bc\u3057\u3057\u3066\u304f\u308c\u305f\u3053\u3068\u306f\u9593\u9055\u3044\u306a\u3044\u3068\u75db\u611f\u3057\u3066\u3044\u308b\u3002\u4f8b\u3048\u3070\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\uff08MIP\uff09\u306f\u3001\u7121\u810a\u690e\u52d5\u7269\u306b\u3082\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\u304c\u5b58\u5728\u3059\u308b\u3053\u3068\u304c\u521d\u3081\u3066\u8a3c\u660e\u3055\u308c\u305f\u6642\u306b\u898b\u3064\u304b\u3063\u305f\u3082\u306e\u3067\u3042\u308a\u3001\u898b\u3064\u3051\u305f\u306e\u306f\u5148\u8ff0\u306e\u30a2\u30e0\u30b9\u30c6\u30eb\u30c0\u30e0\u81ea\u7531\u5927\u5b66\u306e\u7814\u7a76\u8005\u3067\u3042\u3063\u305f\u3002\u3064\u307e\u308a\u7814\u7a76\u306f\u3001\u9650\u308a\u306a\u304f\u53d7\u3051\u7d99\u304c\u308c\u3066\u3044\u304f\u3082\u306e\u3060\u3068\u5f37\u304f\u611f\u3058\u3066\u304a\u308a\u3001\u5148\u4eba\u305f\u3061\u306b\u611f\u8b1d\u3059\u308b\u6b21\u7b2c\u3067\u3042\u308b\u3002<\/p>","protected":false},"excerpt":{"rendered":"\u516c\u76ca\u793e\u56e3\u6cd5\u4eba\u3000\u65e5\u672c\u52d5\u7269\u5b66\u4f1a\u7406\u4e8b\u4f1a\u306f\u30012018\u5e746\u67082\u65e5\uff08\u91d1\uff09\u7406\u4e8b\u4f1a\u3092\u958b\u50ac\u3057\u3001\u5b66\u4f1a\u8cde\u7b49\u9078\u8003\u59d4\u54e1\u4f1a\u306e\u63a8\u85a6\u5019\u88dc\u8005\u3092\u57fa\u306b\u3001\u5404\u8cde\u53d7\u8cde\u8005\u306e\u5be9\u8b70\u884c\u3044\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u5e73\u621029\u5e74\u5ea6\u65e5\u672c\u52d5\u7269\u5b66\u4f1a\u306e\u5404\u8cde\u3092\u4e0b\u8a18\u306e\u3088\u3046\u306b\u6c7a\u5b9a\u3057\u307e\u3057\u305f\u3002\u6388\u8cde\u5f0f\u3001\u307e [&hellip;]","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[42,12],"tags":[],"class_list":["post-2012","post","type-post","status-publish","format-standard","hentry","category-topics","category-zs-award"],"acf":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/pb55P2-ws","_links":{"self":[{"href":"https:\/\/www.zoology.or.jp\/english\/wp-json\/wp\/v2\/posts\/2012","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.zoology.or.jp\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.zoology.or.jp\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.zoology.or.jp\/english\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.zoology.or.jp\/english\/wp-json\/wp\/v2\/comments?post=2012"}],"version-history":[{"count":1,"href":"https:\/\/www.zoology.or.jp\/english\/wp-json\/wp\/v2\/posts\/2012\/revisions"}],"predecessor-version":[{"id":2013,"href":"https:\/\/www.zoology.or.jp\/english\/wp-json\/wp\/v2\/posts\/2012\/revisions\/2013"}],"wp:attachment":[{"href":"https:\/\/www.zoology.or.jp\/english\/wp-json\/wp\/v2\/media?parent=2012"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.zoology.or.jp\/english\/wp-json\/wp\/v2\/categories?post=2012"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.zoology.or.jp\/english\/wp-json\/wp\/v2\/tags?post=2012"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}